Thessaloniki, 1917. As Dimitri Komninos is born, a fire sweeps through the thriving multicultural city, where Christians, Jews and Moslems live side by side. It is the first of many catastrophic events that will change forever this city, as war, fear and persecution begin to divide its people. Five years later, young Katerina escapes to Greece when her home in Asia Minor is destroyed by the Turkish army. Losing her mother in the chaos, she finds herself on a boat to an unknown destination. From that day the lives of Dimitri and Katerina become entwined, with each other and with the story of the city itself.